Updates to Mike’s Biostatistics Book

September 2025.

Mike’s Biostatistics Book additions of late:

  • Added more than 70 figures since Fall 2024.
  • Added more than 100 true/false and multiple choice questions to my end of chapter quizzes. Quizzes generate immediate “Correct” or “Wrong” responses. 
    • Chapters covered: Ch01, Ch02, Ch03, parts of Ch04 and Ch06.7
    • Expect to add about another 100 questions by end of October.
  • Updated install R instructions to R version 4.5.1
  • Added new instructions for R use in Google Colaboratory.

/MD

Mike’s Biostatistics Book now at LibreTexts

Mike’s Biostatistics Book, my open textbook I use to support my biostatistics course at Chaminade University, was adopted (September 2024) by the folks at LibreTexts and is now available as part of their open educational resource library in the Applied Statistics. The link is https://stats.libretexts.org/Bookshelves/Applied_Statistics/Mike%E2%80%99s_Biostatistics_Book_(Dohm)

LibreTexts Mike's Biostatistics BookThe primary version of Mike’s Biostatistics Book will remain here at my letgen.org website, but the LibreTexts version will also be maintained, and may well be a more attractive vehicle for others to use, or if instructors, even adopt for their courses. Future plans include moving homework and related tutorial resources, which are primarily the purpose of my companion site, Mike’s Workbook for Biostatistics, to the LibreText open homework system

Because of the copy right license under which I’ve released my textbook, end users are also free to correct typos, any content errors, or even edit the text to suit their own needs, provided that that my name remains attached to the text.

Wikipedia has a nice summary about LibreTexts.A nice writeup about Open Access textbooks and LibreTexts by E. Wexler (2017) is available at EdSurge.

Summer reading list

Suggested light reading for undergraduate and graduate biology students

1491 (Second Edition): New Revelations of the Americas Before ColumbusCharles C. Mann
A Brief History of Everyone Who Ever Lived: The Human Story Retold Through Our GenesAdam Rutherford
A Crack In Creation: Gene Editing and the Unthinkable Power to Control EvolutionJennifer A. Doudna and Samuel H. Sternberg
Bad Blood: Secrets and Lies in a Silicon Valley StartupJohn Carreyrou
Bully for Brontosaurus: Reflections in Natural HistoryStephen Jay Gould
Empire of Pain: The Secret History of the Sackler DynastyPatrick Radden Keefe
Enlightenment Now: The Case for Reason, Science, Humanism and progressSteven Pinker
Finding Darwin’s God: A Scientist’s Search for Common Ground Between God and EvolutionKenneth R. Miller
Galileo’s Middle Finger: Heretics, Activists, and One Scholar’s Search for JusticeAlice Dreger
Herding Hemingway’s Cats: Understanding how our genes workKat Arney
Is Science Racist? (Debating Race)Jonathan Marks
Life’s Greatest Secret: The Story of the Race to Crack the Genetic CodeMatthew Cobb
Simply Complexity: A Clear Guide to Complexity TheoryNeil Johnson
The Art and Politics of ScienceHarold E. Varmus
The Emperor of All Maladies: A Biography of CancerSiddhartha Mukherjee
The Genome War: How Craig Venter Tried to Capture the Code of Life and Save the WorldJames Shreeve
The Mismeasure of ManStephen Jay Gould
The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving TreatmentJessica Wapner
The Selfish GeneRichard Dawkins
The Society of GenesItai Yanai and Martin Lercher
What’s in your genome?: 90% of your genome is junkLawrence Moran
Weapons of Math Destruction: How Big Data Increases Inequality and Threatens DemocracyCathy O’Neil
Why Big Fierce Animals Are Rare: An Ecologist’s PerspectivePaul A. Colinvaux
Why Evolution is TrueJerry A. Coyne

Install WSL and Ubunto distro on Windows 10

Notes activating Windows Subsystem for Linux (WSL) and installing Ubuntu (ver 20.04 LTS) on my Windows 10 Home (21H1) PC.

Modified from

Note also includes instructions to install Homebrew

Enable WSL

  1. Open PowerShell as Administrator
  2. Run at command line
    dism.exe /online /enable-feature /featurename:Microsoft-Windows-Subsystem-Linux /all /norestart

Enable Virtual Machine platform

  1. Assuming system meets requirements for WSL2, proceed to enable virtual machine platform. Run at command line
    dism.exe /online /enable-feature /featurename:VirtualMachinePlatform /all /norestart
  2. Download wsl_update_x64.msi.
  3. Restart PC to complete WSL install and update WSL2.

Install update package

  1. Run wsl_update_x64.msi, the Linux kernel package. Follow instructions as presented.

Set WSL 2 as default version

  1. Open Powershell as Administrator. Run
    wsl --set-default-version 2

Get Linux distro from Microsoft Store.

  1. I installed Ubuntu 20.04 LTS. As of 26 July 2021, Direct url https://www.microsoft.com/store/apps/9n6svws3rx71
  2. After installation, launch UBUNTU (e.g., start menu) to finish Linux setup.

Update Linux

#download package information
sudo apt update
#install packages from sources listed in /etc/apt/sources.list.
sudo apt upgrade

Install Homebrew

https://brew.sh/

/bin/bash -c "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/HEAD/install.sh)"

test install

test -d ~/.linuxbrew && eval $(~/.linuxbrew/bin/brew shellenv)
test -d /home/linuxbrew/.linuxbrew && eval $(/home/linuxbrew/.linuxbrew/bin/brew shellenv)
test -r ~/.bash_profile && echo "eval \$($(brew --prefix)/bin/brew shellenv)" >>~/.bash_profile
echo "eval \$($(brew --prefix)/bin/brew shellenv)" >>~/.profile

Update gcc

brew install gcc

Only 27% of trademark with Aloha located Hawaii

Google Data Studio report of “Aloha” as part of trademark. Data collected from TESS, United States Patent and Trademark Office.

  • As of June 2020, only 27% of the 539 live trademarks that incorporate “aloha” as part of the trademark name are registered to an address in Hawai’i.
  • updated 8 Jan 2021: Microsoft Edge browser default Tracking Prevention (“Balanced”) settings may not render Google Data Studio data correctly.
    • Optional, change Tracking Prevention settings from “Balanced” to “Basic”.
    • PDF version available: Aloha_trademarks

Cultural appropriation of Hawai’i values

Following the Aloha poke and Salesforce ohana controversies, I wanted to present a data view of how much of Hawaii is incorporated into trademarks of business products and services.  I don’t claim that all non-Hawaiian registrations represent appropriation (as opposed to honoring) culture,  but offer the work only as a means to track. Please visit other sites better positioned to discuss appropriation of Hawaii culture. For example:

7 June 2020, M. Dohm, Chaminade University

Laboratory of Environmental Toxicology and Genomics